![]() No other lifestyle related factors were risk factors. Age was found to be a risk factor for antacid medications in both groups ( p = 0.002, p = 0.007). Results: Of the 420 patients, 272 were in the middle-aged group and 148 patients in the older age group. ![]() The relationships between antacid medications and patient lifestyle and comorbidities were evaluated by multivariate analyses. The subjects were allocated to middle-aged (55–69 years) and older age groups (70–89 years). Exclusion criteria comprised low-dose aspirin and/or nonsteroidal anti-inflammatory drugs. They were aged from 55 to 89 years, had no upper gastrointestinal lesions detected by endoscopy, and no H. Methods: This cross-sectional study included the patients who underwent upper gastrointestinal endoscopy in our institution between August 2017 and July 2018. Objective: The aim of this study was to determine the characteristics of patients without Helicobacter pylori infection who were prescribed antacid medications (potassium-competitive acid blockers, proton pump inhibitors, and/or H 2 receptor antagonist) and had no upper gastrointestinal lesions detected by endoscopy.
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